Immunohistochemical staining of USP10 and MSH2 proteins in representative lung squamous cell carcinoma and lung adenocarcinoma tissue specimens. (A-D) The expression of USP10 in representative tumor cells of lung squamous cell carcinoma. (A) Score=3. (B) Score=2. (C) Score=1. (D) Score=0. (E-H) The expression of MSH2 in representative tumor cells of lung squamous cell carcinoma. (E) Score=3+. (F) Score=2+. (G) Score=1+. (H) Score=0. (I-L) The expression of USP10 in representative tumor cells of lung adenocarcinoma. (I) Score=3. (J) Score=2. (K) Score=1. (L) Score=0. (M-P) The expression of MSH2 in representative tumor cells of lung adenocarcinoma (M) Score=3+. (N) Score=2+. (O) Score=1+. (P) Score=0. 3,3′-Diaminobenzidine staining (brown); nuclear counterstaining (hematoxylin). Original magnification, ×100. Score ≤1 or 1+ was defined as negative expression of USP10 or MSH2, score >1 or 1+ was defined as positive expression of USP10 or MSH2. MSH2, MutS homolog 2; USP10, ubiquitin-specific protease 10.