Kaplan-Meier survival analysis of USP10 and MSH2 protein and mRNA expression in tumor cells of NSCLC (log-rank test). (A) Association between USP10 protein expression in NSCLC and overall survival (P>0.05). USP10 negative expression (n=27); USP10 positive expression (n=29). (B) Association between MSH2 protein expression in NSCLC and overall survival (P>0.05). MSH2 negative expression (n=10), MSH2 positive expression (n=46). (C) Association between USP10 mRNA expression in lung squamous cell carcinoma and overall survival, from TCGA database (P>0.05). USP10 negative expression (n=369); USP10 positive expression (n=125). (D) Association between MSH2 mRNA expression in lung squamous cell carcinoma and overall survival, from TCGA database (P>0.05). MSH2 negative expression (n=370); MSH2 positive expression (n=124). (E) Association between USP10 mRNA expression in lung adenocarcinoma and overall survival, from TCGA database (P>0.05). USP10 negative expression (n=376); USP10 positive expression (n=126). (F) Association between MSH2 mRNA expression in lung adenocarcinoma and overall survival (P>0.05), from TCGA database. MSH2 negative expression (n=375); MSH2 positive expression (n=127). MSH2, MutS homolog 2; USP10, ubiquitin-specific protease 10; NSCLC, non-small cell lung cancer; TCGA, The Cancer Genome Atlas.