Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 7;41(2):853–862. doi: 10.3892/or.2018.6915

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Kataoka et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Galectin-3 promotes NSCLC cell migration and invasion under hypoxia. The effect of hypoxia-induced galectin-3 on Wt cells and cells transfected with galectin-3 shRNA (Gal3 shRNA #1, #2) or scrambled control shRNA (scr #1, #2) on cell migration and invasion in NSCLC cells (A549 and LK-2) was assessed by a (A) scratch and an (B) invasion assays. (C) A549 and LK-2 cells transfected with galectin-3 shRNA were cultured with the indicated concentrations of recombinant galectin-3 (r-gal3) under hypoxic conditions (H; 1% O₂). Cell migration was assessed by scratch assay. The results from each assay are summarized in the accompanying histograms. *P<0.05; **P<0.01; N.S., not significant. Wt, wild-type; N, normoxic condition (21% O₂); H, hypoxic condition (2% O₂); NSCLC, non-small cell lung cancer.