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. 2018 Nov 9;41(2):779–788. doi: 10.3892/or.2018.6860

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Copyright: © Lu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — PP2A forms a complex with CDK5. (A and B) IP and Coomassie bright blue staining followed by liquid phase mass spectrometry were performed to identify potential targets of CDK5 in HGC-27 gastric cancer cells. (C) Western blot analysis revealed that CDK5 interacted with PP2A. CDK5, cyclin dependent kinase 5; PP2A, serine/threonine-protein phosphatase 2A; IP, immunoprecipitation; EGFP, enhanced green fluorescent protein; WT, wild-type; NLS, nuclear localisation signal; NES, nuclear export signal; DOX, doxycycline.