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. 2018 Nov 9;41(2):753–764. doi: 10.3892/or.2018.6859

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Copyright: © Hou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — TROP2 is upregulated in human glioblastoma and is a prognostic indicator for glioblastoma patients. (A) Representative immunohistochemical assays of TROP2 expression in human glioblastoma (right) and adjacent normal brain tissue (left). (B) Immunohistochemical analyses of TROP2 expression in 8 paired samples of glioblastoma and normal brain tissue, P<0.001. (C) Western blot analyses were performed to detect TROP2 expression in human normal astroglial cells (SVGP12), four glioblastoma cell lines (A172, LN-229, U-87 MG and U-118 MG), normal brain tissues and glioblastoma tissues. (D and E) Kaplan-Meier analysis of progression-free survival using data from the Tumor Glioma-kawaguchi-50 database and Tumor Glioma-French-284 database with the log-rank test P-values indicated. TROP2, trophoblast cell surface antigen 2.