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. 2018 Nov 9;41(2):753–764. doi: 10.3892/or.2018.6859

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Copyright: © Hou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — TROP2 promotes migration and invasion of glioblastoma cells. (A) The expression of TROP2 mRNA in TROP2-knockdown U-87 MG and LN-229 cell lines and negative controls were detected by PCR analysis. GAPDH served as endogenous control. (B) The expression of TROP2 protein in TROP2-knockdown U-87 MG and LN-229 cell lines and negative controls were detected by western blot analysis. GAPDH served as loading control. (C) Migration and (D) invasion assays were performed in TROP2-knockdown U-87 MG and LN-229 cells and negative controls. All data are shown as the means ± SD; **P<0.01, ***P<0.001. All P-values are based on the control vs. treatment group. TROP2, trophoblast cell surface antigen 2.