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. 2018 Nov 9;41(2):753–764. doi: 10.3892/or.2018.6859

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Copyright: © Hou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — TROP2 promotes self-renewal and tumor growth of glioblastoma cells in vitro and in vivo. (A) The effects of TROP2 on the colony formation in TROP2-knockdown U-87 MG and LN-229 cells. (B) Xenograft assays were performed after TROP2 knockdown in U-87 MG and LN-229 cells. The size and weight of xenograft tumors were analyzed with two-tailed Student's t-test and P-value is indicated. (C) The growth curve of xenograft tumors was analyzed with with two-tailed Student's t-test and P-value is indicated. All data are shown as the means ± SD; *P<0.05, **P<0.01, ***P<0.001. All P-values are based on control vs. treatment group. TROP2, trophoblast cell surface antigen 2.