Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 9;41(2):753–764. doi: 10.3892/or.2018.6859

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Hou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 7. — Exogenous IL-6 reverses phenotype changes of TROP2-silenced glioblastoma cells. (A) Western blot analysis of JAK2^Tyr1007/1008, total JAK2, STAT3^Tyr705 and total STAT3 levels in control cells and TROP2-knockdown cells with or without IL-6 exposure. GAPDH was used as loading control. (B and C) Qualification of the data for migration and invasion assays in control cells and TROP2-knockdown cells with or without IL-6 exposure. (D) MTT assays were performed to examine cell viability of control cells and TROP2-knockdown cells with or without IL-6 exposure. (E) Representative images of colony formation assay for control cells and TROP2-knockdown cells with or without IL-6 exposure. All data are shown as the means ± SD; *P<0.05, **P<0.01. All P-values are based on control vs. treatment group. IL-6, interleukin 6; TROP2, trophoblast cell surface antigen 2.