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. 2018 Dec 4;41(2):939–953. doi: 10.3892/or.2018.6901

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Diagnostic value of miRNA-126-3p and miRNA-126--5p for LUAD according to RT-qPCR. (A) Expression of miRNA-126-3p in 101 LUAD tissues and 101 adjacent normal lung tissues (3.511±2.118 vs. 6.674±3.362, P<0.001). (B) Expression of miRNA-126-5p in 101 LUAD tissues and 101 adjacent normal lung tissues (4.271±2.501 vs. 6.314±3.289, P<0.001). (C) ROC curve of miRNA-126-3p for LUAD based on the 101 LUAD tissues and 101 adjacent normal lung tissues (AUC=0.793, P<0.001). (D) ROC curve of miRNA-126-5p for LUAD based on the 101 LUAD tissues and 101 adjacent normal lung tissues (AUC=0.689, P<0.001). (E) Combined ROC curve of miRNA-126-3p and −5p for LUAD based on the 101 LUAD tissues and 101 adjacent normal lung tissues (AUC=0.821, P<0.001). LUAD, lung adenocarcinoma; AUC, area under the receiver operating characteristic (ROC) curve.