Table I.
Average diameter of tumor (cm) | ||||
---|---|---|---|---|
Time (day) | siNC | siRNA | siNC+10 mg/kg | siRNA+10 mg/kg |
9 | 0.34±0.06 | 0.42±0.06 | 0.08±0.01a,b | 0.22±0.04b |
12 | 0.57±0.05 | 0.73±0.08 | 0.12±0.02a,b | 0.34±0.05b |
15 | 0.77±0.07 | 0.96±0.09a | 0.21±0.04a,b | 0.47±0.07b |
18 | 0.90±0.08 | 1.29±0.10a | 0.30±0.05a,b | 0.53±0.09b |
21 | 1.02±0.11 | 1.65±0.14a | 0.39±0.05a | 0.62±0.12b |
P<0.05 vs. siNC
P<0.05 vs. siRNA; si, small interfering RNA; NC, negative control.