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Depletion of CIP2A induces apoptosis. (A) Cisplatin significantly potentiated apoptosis in chemosensitive SKOV-3 cells transfected with either CIP2A or control siRNA. (B) CIP2A silencing significantly potentiated the apoptosis induced by cisplatin in chemoresistant SKOV-3CDDP/R cells with CIP2A knockdown compared with chemoresistant SKOV-3CDDP/R cells transfected with control siRNA. **P<0.01 CIP2A, cancerous inhibitor of protein phosphatase 2A; siRNA, small interfering RNA.
