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. 2018 May 21;22(1):1–9. doi: 10.1093/ijnp/pyy042

Figure 1.

Figure 1.

(A) sagittal-oblique T1-weighted MRI of the brain showing sample coregistration of FreeSurfer right insula volume-of-interest (yellow-red) with superimposed right perisylvian 1H magnetic resonance spectroscopic imaging (MRSI) point-resolved spectroscopy (PRESS) excitation volume (“slice,” white rectangle). A similar sagittal-oblique PRESS slice sampled the left insula. (B) Overlap of the right insula volume with a third, axial-oblique PRESS slice. The opposite side of this slice cosampled the left insula. Each slice was 9 mm thick and consisted of a rectangular in-plane array of 11×11 mm2 voxels (green grids). (C) Sample right perisylvian MRSI spectrum showing high-amplitude, low-noise, well-separated peaks for the target neurometabolites N-acetyl-aspartate+N-acetyl-aspartyl-glutamate (tNAA) and glutamate+glutamine (Glx).