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GIT1 was confirmed to be a direct target of miR-149-5p in MTC. (A) The binding sites of miR-149-5p on the 3′-UTR of GIT1. (B) Luciferase reporter assay. (C and D) The mRNA and protein expression levels of GIT1 were analyzed in cells containing miR-149-5p mimics or inhibitor. (E) Kaplan-Meier overall survival curves of MTC patients. High GIT1 expression was related to shorter OS of MTC patients. *P<0.05, **P<0.01.
