Table V.
KEGG pathway analysis of the target genes of miR-21-5p.
| KEGG ID | Name | Count | FDR | Gene symbol |
|---|---|---|---|---|
| hsa04060 | Cytokine-cytokine receptor interaction | 6 | 0.00262 | CCR1, CXCL12, HGF, IL6ST, NGFR, PDGFRA |
| hsa04015 | Rap1 signaling pathway | 5 | 0.00393 | HGF, NGFR, PDGFRA, TEK, THBS1 |
| hsa04151 | PI3K-Akt signaling pathway | 6 | 0.00393 | HGF, NGFR, PDGFRA, TEK, THBS1, TLR4 |
| hsa05144 | Malaria | 3 | 0.00659 | HGF, THBS1, TLR4 |
| hsa05206 | MicroRNAs in cancer | 4 | 0.00894 | PDGFRA, SPRY2, THBS1, ZEB2 |
| hsa05202 | Transcriptional misregulation in cancer | 4 | 0.0126 | DUSP6, FOXO1, IGFBP3, NGFR |
| hsa05215 | Prostate cancer | 3 | 0.0204 | AR, FOXO1, PDGFRA |
| hsa05323 | Rheumatoid arthritis | 3 | 0.0204 | CXCL12, TEK, TLR4 |
| hsa04014 | Ras signaling pathway | 4 | 0.0225 | HGF, NGFR, PDGFRA, TEK |
| hsa05205 | Proteoglycans in cancer | 4 | 0.0225 | ESR1, HGF, THBS1, TLR4 |
KEGG, Kyoto Encyclopedia of Genes and Genomes; FDR, false discovery rate.