Table III.
Change in body composition by genotypes.
| Polymorphism | β for the slope of skeletal musclea,b | P | β for the slope of ECWa,b | P |
|---|---|---|---|---|
| IL-1B C-31T (rs1143627) | 0.172 (−0.100, 0.445) | 0.211 | 0.0077 (−0.0963, 0.1116) | 0.883 |
| IL-1RN VNTR | −0.681 (−1.064, −0.299) | 0.001 | 0.0208 (−0.1385, 0.1801) | 0.795 |
| IL-6 C-634G (rs1800796) | −0.040 (−0.367, 0.288) | 0.809 | 0.0007 (−0.0051, 0.0019) | 0.245 |
| IL-8 T-251A (rs4073) | −0.175 (−0.458, 0.107) | 0.219 | 0.0059 (−0.1019, 0.1136) | 0.913 |
| IL-10 T-819C (rs3021097) | −0.117 (−0.410, 0.176) | 0.427 | 0.1119 (−0.0051, 0.2187) | 0.040 |
| IL-10 A-1082G (rs1800896) | −0.267 (−0.858, 0.325) | 0.370 | 0.0036 (−0.2204, 0.2277) | 0.974 |
a
β-values for the slope of each body composition element per allele (additive) model were calculated using linear regression; ECW, extra-cellular water (in proportion to the total body weight).
b
Monthly body composition data was available in 58 subjects.