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. 2018 Oct 29;17(1):603–615. doi: 10.3892/ol.2018.9629

Figure 5.

Figure 5.

Figure 5.

Figure 5.

Effects of the combination of 5 µg/ml paclitaxel and mild hyperthermia on the apoptotic ratio of MCF-7 cells. Flow cytometry of MCF-7 cells using an Annexin V-FITC/PI cell apoptosis staining kit at (A) 24 h post-treatment or (B) 48 h post-treatment. (C) Apoptotic ratios (% apoptotic cells) at 24 and 48 h post-treatment at varying temperatures. *P<0.01 vs. control; #P<0.01, vs. hyperthermia alone; &P<0.05 vs. chemotherapy alone; +P<0.05 vs. combined therapy; ##P<0.01 vs. 40.5°C; &&P<0.05 vs. 40.5°C combined therapy; $P<0.05 vs. 24 h. FITC, fluorescein isothiocyanate; PI, propidium iodide; Ptx, paclitaxel.