Table I.
TERT mutations | ||||
---|---|---|---|---|
Variable | Total number | Mut | WT | P-value |
Number | 179 | 97 | 82 | |
Age (years) | ||||
≤48.5 | 71 | 46 | 25 | 0.038 |
>48.5 | 108 | 72 | 36 | |
Sex | ||||
Male | 108 | 58 | 50 | 0.253 |
Female | 71 | 31 | 40 | |
WHO grade | ||||
II | 38 | 17 | 21 | 0.015 |
III | 43 | 26 | 17 | |
IV | 98 | 54 | 44 | |
IDH | ||||
Mut | 73 | 35 | 38 | 0.066 |
WT | 106 | 62 | 44 | |
ATRX | ||||
Expression | 128 | 86 | 37 | 0.001 |
Loss | 50 | 11 | 39 | |
Ki-67 expression (%) | ||||
≤27.12a | 88 | 45 | 43 | 0.167 |
>27.12 | 91 | 53 | 38 | |
Recurrence (n) | ||||
Recurrence | 8 | 5 | 3 | 0.442 |
Non-recurrence | 180 | 93 | 87 |
Mean of Ki-67 expression is 27.12%. TERT, telomerase reverse transcriptase; WHO, world health organization; IDH, isocitrate dehydrogenase; ATRX, α thalassemia/mental retardation syndrome X-linked; Mut, mutation; WT, wild-type.