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. 2018 Oct 29;17(1):95–102. doi: 10.3892/ol.2018.9634

Table I.

Associations between various factors and TERT status.

TERT mutations

Variable Total number Mut WT P-value
Number 179 97 82
Age (years)
  ≤48.5 71 46 25 0.038
  >48.5 108 72 36
Sex
  Male 108 58 50 0.253
  Female 71 31 40
WHO grade
  II 38 17 21 0.015
  III 43 26 17
  IV 98 54 44
IDH
  Mut 73 35 38 0.066
  WT 106 62 44
ATRX
  Expression 128 86 37 0.001
  Loss 50 11 39
Ki-67 expression (%)
  ≤27.12a 88 45 43 0.167
  >27.12 91 53 38
Recurrence (n)
  Recurrence 8 5 3 0.442
  Non-recurrence 180 93 87
a

Mean of Ki-67 expression is 27.12%. TERT, telomerase reverse transcriptase; WHO, world health organization; IDH, isocitrate dehydrogenase; ATRX, α thalassemia/mental retardation syndrome X-linked; Mut, mutation; WT, wild-type.