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. 2018 Oct 16;17(1):323–331. doi: 10.3892/ol.2018.9584

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Cell apoptosis was decreased by HBV-associated exosomes in a concentration-dependent manner. (A) Cells were treated with 1×10¹⁰, 2×10¹⁰ or 4×10¹⁰ HBV-associated exosomes, and the expression of cleaved caspase-3 and Bcl-2 was assessed by western blotting. (B) Flow cytometry results indicated that cell apoptosis was negatively associated with the concentration of HBV-associated exosomes. HBV, hepatitis B virus; Bcl-2, B-cell lymphoma; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; Exo, exosome; Oxa, oxaliplatin; UR, upper right; LR, lower right; Ctr, control; PBS, phosphate-buffered saline.