Table 4.
Factor scores of general, non‐affective, affective and specific symptom dimensions by socio‐demographic and clinical variables
| General | Non‐affective | Affective | Positive symptoms | Negative symptoms | Disorganization | Mania | Depression | |
|---|---|---|---|---|---|---|---|---|
| B (95% CI), p | B (95% CI), p | B (95% CI), p | B (95% CI), p | B (95% CI), p | B (95% CI), p | B (95% CI), p | B (95% CI), p | |
| Age | –0.00 (–0.01 to 0.00), 0.167 | –0.01 (–0.01 to 0.00), 0.001 | 0.01 (0.00 to 0.01), 0.017 | 0.01 (0.00 to 0.01), 0.010 | 0.00 (–0.00 to 0.01), 0.282 | 0.01 (0.01 to 0.01), <0.001 | 0.00 (–0.00 to 0.01), 0.401 | –0.00 (–0.01 to 0.00), 0.356 |
| Gender | ||||||||
| Women vs. men | 0.09 (–0.04 to 0.22), 0.156 |
–0.33 (–0.44 to –0.22), <0.001 |
0.26 (0.15 to 0.38), <0.001 |
–0.16 (–0.27 to –0.05), 0.006 |
–0.02 (–0.14 to 0.09), 0.683 | –0.07 (–0.17 to 0.03), 0.179 | –0.02 (–0.13 to 0.09), 0.684 | 0.22 (0.10 to 0.34), 0.001 |
| Ethnicity | ||||||||
| African American vs. Caucasian | 0.22 (0.09 to 0.35), 0.001 | 0.05 (–0.08 to 0.17), 0.456 | –0.04 (–0.17 to 0.08), 0.487 | 0.23 (0.11 to 0.35), <0.001 | 0.16 (0.03 to 0.29), 0.013 | 0.20 (0.09 to 0.30), <0.001 | 0.00 (–0.11 to 0.12), 0.977 |
–0.16 (–0.30 to –0.03), 0.017 |
| Other vs. Caucasian | 0.02 (–0.24 to 0.28), 0.855 | 0.00 (–0.24 to 0.24), 0.976 | 0.02 (–0.22 to 0.26), 0.858 | 0.22 (–0.02 to 0.45), 0.071 | 0.12 (–0.12 to 0.37), 0.325 | 0.06 (–0.14 to 0.27), 0.554 | –0.10 (–0.33 to 0.13), 0.377 | 0.09 (–0.17 to 0.35), 0.489 |
| Social functioning |
–0.01 (–0.01 to –0.00), <0.001 |
–0.00 (–0.01 to –0.00), 0.023 |
–0.00 (–0.01 to –0.00), 0.020 |
–0.01 (–0.01 to –0.01), <0.001 |
–0.01 (–0.02 to –0.01), <0.001 |
–0.01 (–0.01 to –0.00), <0.001 |
0.01 (0.01 to 0.01), <0.001 |
–0.01 (–0.01 to –0.00), <0.001 |
| DSM diagnosis | ||||||||
| Schizoaffective vs. bipolar disorder | 0.34 (0.17 to 0.50), <0.001 | 0.27 (0.13 to 0.41), <0.001 | 0.15 (0.01 to 0.30), 0.042 | 0.87 (0.74 to 1.00), <0.001 | 0.58 (0.43 to 0.73), <0.001 | 0.46 (0.33 to 0.58), <0.001 | –0.30 (–0.48 to –0.15), <0.001 | 0.29 (0.13 to 0.45), <0.001 |
| Schizophrenia vs. bipolar disorder | 0.06 (–0.09 to 0.21), 0.417 | 0.70 (0.58 to 0.83), <0.001 |
–0.40 (–0.54 to –0.28), <0.001 |
0.75 (0.63 to 0.87), <0.001 | 0.55 (0.42 to 0.68), <0.001 | 0.53 (0.42 to 0.64), <0.001 | –0.24 (–0.37 to –0.12), <0.001 | –0.08 (–0.22 to 0.06), 0.286 |
| B‐SNIP biotypes | ||||||||
| Biotype 2 vs. biotype 1 | 0.16 (–0.01 to 0.34), 0.070 | –0.13 (–0.29 to 0.04), 0.132 | 0.19 (0.03 to 0.35), 0.022 | –0.09 (–0.25 to 0.07), 0.283 | –0.05 (–0.22 to 0.12), 0.574 |
–0.16 (–0.30 to –0.01), 0.033 |
–0.01 (–0.16 to 0.15), <0.924 | 0.11 (–0.06 to 0.29), <0.001 |
| Biotype 3 vs. biotype 1 | 0.03 (–0.14 to 0.20), 0.712 |
–0.37 (–0.53 to –0.22), <0.001 |
0.12 (–0.03 to 0.28), 0.117 |
–0.26 (–0.42 to –0.11), 0.001 |
–0.21 (–0.37 to –0.05), 0.010 |
–0.30 (–0.44 to –0.16), <0.001 |
0.02 (–0.12 to 0.17), 0.751 | 0.13 (–0.04 to 0.29), 0.129 |
B‐SNIP – Bipolar‐Schizophrenia Network on Intermediate Phenotypes