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The biochemical, physiochemical and mechano-structural cues along with their factors present in the cellular microenvironment
| Cue | Factors |
|---|---|
| Biochemical | Cytokines |
| Other cells | |
| Hormones | |
| Nutrients | |
| pH | |
| Physio-chemical | Oxygen |
| Temperature | |
| Surface energy | |
| Flow | |
| Mechano-structural | Shear stress |
| Strain | |
| Stiffness | |
| Roughness | |
| Topography | |
| Architecture |
