Figure 12.

Combination effects of anticancer drugs and dental medicines on the augmentation of the cytotoxicity of BA (upper column) and SBA (lower column). HSC-2 cells were incubated for 48 h with the indicated concentrations of drugs in the presence of 0, 1, 2, 4, 8, or 16 mM BA or SBA, and the viable cell number was determined by MTT methods. Each value represents mean ± S.D. of triplicate assays. DXR, doxorubicin; MMC, mitomycin C; MTX, methotrexate; 5-FU, 5-fluorouracil; DTX, docetaxel; NaF, sodium fluoride.