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. 2018 Nov 14;8(4):37. doi: 10.3390/jpm8040037

Table 1.

The distributions of Kv-associated single nucleotide polymorphisms (SNPs) in 296 epileptic patients and 299 healthy controls.

Gene SNP ID Model Cases (%) Controls (%) OR (95% CI) p-Value *
KCNA1 rs2227910 CC/GC/GG 41.1/40.4/18.5 38.6/45.0/16.4 _ 0.52
CC/(GC + GG) 41.1/58.9 38.6/61.4 0.90 (0.65−1.25) 0.53
(CC + GC)/GG 81.5/18.5 83.6/16.4 1.15 (0.75−1.76) 0.51
rs112561866 GA 0.0 0.3 _ 0.24
rs7974459 CC/TC/TT 40.5/43.7/15.8 39.6/41.0/19.4 1.04 (0.72−1.50) 0.54
CC/(TC + TT) 40.5/59.5 39.6/60.4 0.97 (0.69−1.35) 0.84
(CC + TC)/TT 84.2/15.8 80.7/19.3 0.79 (0.51−1.21) 0.28
KCNA2 rs3887820 CC/CA/AA 79.8/18.5/1.7 82.9/15.4/1.7 _ 0.6
CC/(CA + AA) 79.8/20.2 82.9/17.1 1.23 (0.81−1.87) 0.33
(CC + CA)/AA 98.3/1.7 98.3/1.7 1.00 (0.29−3.50) 1
KCNV2 rs7029012 GG/GC/CC 37.7/47.4/14.9 37/47.5/15.5 0.94 (0.66−1.35) 0.98
GG/(GC + CC) 37.7/62.3 37/63 1.02(0.73−1.43) 0.91
(GG + GC)/CC 85.1/14.9 84.5/15.5 1.04(0.66−1.63) 0.87
rs10967705 GG/CG/CC 34.4/50.3/15.3 35.5/49.1/15.4 _ 0.95
GG/(CG + CC) 34.3/65.7 35.5/64.5 1.05 (0.75−1.47) 0.78
(GG + CG)/CC 84.7/15.3 84.6/15.4 0.99 (0.64−1.55) 0.98
rs10967728 GG/GC/CC 31.0/48.3/20.7 27.8/49.6/22.6 _ 0.67
GG/(GC + CC) 31.0/69.0 27.8/72.2 0.85 (0.60−1.22) 0.39
(GG + GC)/CC 79.3/20.7 77.4/22.6 0.89 (0.60−1.33) 0.58

* Chi-Square Test with p-value < 0.05 is considered significant. OR: odds ratio; CI: confidence interval.