Table 1.
Gene | SNP ID | Model | Cases (%) | Controls (%) | OR (95% CI) | p-Value * |
---|---|---|---|---|---|---|
KCNA1 | rs2227910 | CC/GC/GG | 41.1/40.4/18.5 | 38.6/45.0/16.4 | _ | 0.52 |
CC/(GC + GG) | 41.1/58.9 | 38.6/61.4 | 0.90 (0.65−1.25) | 0.53 | ||
(CC + GC)/GG | 81.5/18.5 | 83.6/16.4 | 1.15 (0.75−1.76) | 0.51 | ||
rs112561866 | GA | 0.0 | 0.3 | _ | 0.24 | |
rs7974459 | CC/TC/TT | 40.5/43.7/15.8 | 39.6/41.0/19.4 | 1.04 (0.72−1.50) | 0.54 | |
CC/(TC + TT) | 40.5/59.5 | 39.6/60.4 | 0.97 (0.69−1.35) | 0.84 | ||
(CC + TC)/TT | 84.2/15.8 | 80.7/19.3 | 0.79 (0.51−1.21) | 0.28 | ||
KCNA2 | rs3887820 | CC/CA/AA | 79.8/18.5/1.7 | 82.9/15.4/1.7 | _ | 0.6 |
CC/(CA + AA) | 79.8/20.2 | 82.9/17.1 | 1.23 (0.81−1.87) | 0.33 | ||
(CC + CA)/AA | 98.3/1.7 | 98.3/1.7 | 1.00 (0.29−3.50) | 1 | ||
KCNV2 | rs7029012 | GG/GC/CC | 37.7/47.4/14.9 | 37/47.5/15.5 | 0.94 (0.66−1.35) | 0.98 |
GG/(GC + CC) | 37.7/62.3 | 37/63 | 1.02(0.73−1.43) | 0.91 | ||
(GG + GC)/CC | 85.1/14.9 | 84.5/15.5 | 1.04(0.66−1.63) | 0.87 | ||
rs10967705 | GG/CG/CC | 34.4/50.3/15.3 | 35.5/49.1/15.4 | _ | 0.95 | |
GG/(CG + CC) | 34.3/65.7 | 35.5/64.5 | 1.05 (0.75−1.47) | 0.78 | ||
(GG + CG)/CC | 84.7/15.3 | 84.6/15.4 | 0.99 (0.64−1.55) | 0.98 | ||
rs10967728 | GG/GC/CC | 31.0/48.3/20.7 | 27.8/49.6/22.6 | _ | 0.67 | |
GG/(GC + CC) | 31.0/69.0 | 27.8/72.2 | 0.85 (0.60−1.22) | 0.39 | ||
(GG + GC)/CC | 79.3/20.7 | 77.4/22.6 | 0.89 (0.60−1.33) | 0.58 |
* Chi-Square Test with p-value < 0.05 is considered significant. OR: odds ratio; CI: confidence interval.