Table 3.
Distribution of potassium channel related SNPs in the 172 generalized epileptic patients and 299 controls.
| Epilepsy Subtype | SNP ID | Allele/Genotype | Cases N (%) | Controls N (%) | OR (95% CI) | p-Value * |
|---|---|---|---|---|---|---|
| GM | rs7029012 | C | 41 (36) | 240 (41) | 1.00 | 0.15 |
| G | 73 (64) | 352 (59) | ||||
| GG | 20 (35) | 103 (35) | 0.99 (0.54−1.79) | 0.97 | ||
| CG + CC | 37 (65) | 193 (65) | ||||
| GM | rs10967705 | C | 44 (39) | 239 (40) | 1.00 | 0.51 |
| G | 70 (61) | 359 (60) | ||||
| GG | 19 (33) | 106 (35) | 1.10 (0.60−2.00) | 0.76 | ||
| CG + CC | 38 (67) | 193 (65) | ||||
| GM | rs3887820 | C | 55 (48) | 531 (91) | 1.00 | <0.0001 |
| A | 59 (52) | 55 (9) | ||||
| AA | 2 (4) | 10 (1.7) | 1.00 | <0.0001 | ||
| CC + CA | 55 (96) | 288 (98.3) | ||||
| GTC | rs10967728 | G | 125 (56) | 303 (53) | 1.00 | 0.72 |
| C | 99 (44) | 273 (47) | ||||
| GG | 35 (31) | 80 (28) | 0.85 (0.53−1.36) | 0.49 | ||
| GC + CC | 77 (69) | 208 (72) | ||||
| GTC | rs10967705 | G | 135 (59) | 359 (60) | 1.00 | 0.95 |
| C | 93 (41) | 239 (40) | ||||
| GG | 40 (35) | 106 (35) | 1.00 | 0.94 | ||
| GC + CC | 74 (65) | 193 (65) |
* Chi-Square Test with p-value < 0.05 is considered significant. GM: generalized myoclonic seizures, GTC: generalized tonic-clonic seizures.