Figure 6.

Influence of quercetin on the appearance of thioredoxin (TRX) in nasal lavage fluids obtained from OVA-sensitized mice after the OVA nasal challenge. BALB/c mice were sensitized by an intraperitoneal injection of OVA on days 0, 7, and 14. Seven days after the final sensitization, the OVA-sensitized mice were intranasally challenged with OVA on days 21, 23, and 25, and various concentrations of quercetin were administered orally once a day for five consecutive days. Nasal lavage fluids were obtained from the mice 6 h after the nasal antigenic challenge. TRX levels were examined by an ELISA. The data are expressed as the mean ng/ng IgA ± SE of five mice. NS: non-sensitized; IS: intraperitoneal sensitization; NC: nasal challenge alone; QRC: quercetin.