Figure 7.

Influence of quercetin on the development of nasal allergy-like symptoms in OVA-sensitized mice after the OVA nasal challenge. BALB/c mice were sensitized by an intraperitoneal injection of OVA on days 0, 7, and 14. Seven days after the final sensitization, the OVA-sensitized mice were intranasally challenged with OVA on days 21, 23, and 25, and various concentrations of quercetin were administered orally once a day for five consecutive days. Nasal allergy-like symptoms, the number of sneezes (A), and nasal rubbing behaviors (B) were counted for 10 min immediately after the final nasal antigenic challenge. The data are expressed as the mean ± SE of five mice. NS: non-sensitized; IS: intraperitoneal sensitization; NC: nasal challenge alone; QRC: quercetin.