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The effects of Hangeshashinto (HST) and the crude drugs on chemotherapy- and radiotherapy-induced mucositis. HST exerts antioxidative, anti-inflammatory, immunostimulatory, and analgesic effects. Moreover, HST is able to control the symptoms and simultaneously eliminate the underlying causes of the condition. PGE2; prostaglandin E2. COX-2; cyclooxygenase-2.
