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Species-specific immunohistochemical analysis of patient-derived xenograft (PDX) tumour samples. An antibody specific for human mitochondria was used to identify the presence of human cancer cells present in PDX tumours. Representative images of PIN 80 (A,B) and PIN 99 (C,D) show negative staining (A,C) and human species-specific staining of mitochondria (B,D). Antibody-positive cells are marked by dense brown staining in panels (B,D).
