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. 2018 Sep 23;6(4):35. doi: 10.3390/proteomes6040035

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Changes in VTA protein expression in cocaine-treated groups. Volcano plots of proteins in the Cocaine (A) and Cocaine + G-CSF (B) groups relative to saline controls. Log2 Fold change on the x-axis and Log10 p value on the y-axis. Proteins that were significantly changed with a nominal p value of <0.05 are represented by blue dots, and those with a ±20% change and a p < 0.05 are represented by green dots. (C) Demonstrates the changes in the Cocaine + G-CSF group relative to the Cocaine group. Proteins with a nominal p value of <0.05 are represented by turquoise dots, and those with a ± 20% change and a p < 0.05 are represented by red dots.