Figure 2.

Ideal course of protein biomarker research predictive of treatment response. (A) Screening step of a patient cohort to determine a predictive protein biomarker or predictive protein signature. (B) Clinical application of a predictive protein biomarker or predictive protein signature for personalisation of treatment according to the patient. CRC: Colorectal cancer; a: Key features for determining the inclusion parameters of a patient in the cohort, according to a classification detailed in the introduction; b: Patient meeting all of the inclusion criteria defined during the screening step.