Skip to main content
. 2018 Sep 20;6(4):67. doi: 10.3390/vaccines6040067

Figure 4.

Figure 4

Catestatin (CST) increases the activation of p-STAT3 in dextran sulfate sodium (DSS)-induced colitis. Treatment with CST (1.5 mg/kg/day) or 1× phosphate buffer saline (PBS) started one day prior to DSS colitis induction. (A) Colonic phosphorylated levels of p-STAT3 that were quantified using ELISA; and (B) colonic mRNA levels expression of STAT3 were quantified using q-RT-PCR. (C–E) Colonic total and phosphorylated levels of p-STAT3 that were quantified using western blot. One-way ANOVA followed by multiple comparison tests. Each value represents the mean ± SEM, n = 7–10 mice/group. # Refers to significance compared to control groups.