Table 3.

KEGG pathway analysis of differentially expressed genes in patients with diabetic cardiomyopathy.

Category	Term	Count	%	P value	Genes
Downregulated DEGs	hsa04151:PI3K-Akt signaling pathway	8	0.05	0.01	FGF18, CDKN1A, IL6, FGF7, TNC, LAMC2, MYC, and SPP1
	hsa04010:MAPK signaling pathway	6	0.04	0.03	DUSP5, FGF18, FGF7, MAP2K3, FLNC, and MYC
	hsa04066:HIF-1 signaling pathway	4	0.02	0.03	CDKN1A, IL6, and TFRC
	hsa04668:TNF signaling pathway	4	0.02	0.04	IL6, SOCS3, MAP2K3, and SELE
	hsa04620:Toll-like receptor signaling pathway	4	0.02	0.04	IL6, LY96, MAP2K3, and SPP1
Upregulated DEGs	hsa00982:Drug metabolism-cytochrome P450	5	0.03	0.001	FMO4, FMO2, FMO3, ADH1B, and UGT2B4

KEGG: Kyoto Encyclopedia of Genes and Genomes; FDR: false discovery rate.