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. Author manuscript; available in PMC: 2019 Jan 2.
Published in final edited form as: Neurobiol Learn Mem. 2017 Dec 6;147:128–138. doi: 10.1016/j.nlm.2017.11.016

Fig. 4.

Fig. 4

Behavioral data (A) and post-training (after a 3 min post-shock freezing test) IEG expression in the mPFC (B), dHPC (C), and BLA (D) for the HC, Alt-Pre, and Pre experimental groups. (A) The Pre group froze significantly higher than the Alt-Pre group during the 3 min post-shock freezing test (Alt-Pre, p < .001). (B) Immediate-shock training followed by a 3 min post-shock freezing test significantly induced mPFC c-Fos, Arc, and Npas4 expression in the Pre and Alt-Pre groups above HC controls (ps < .05), with an additional associative increase in c-Fos expression (p < .01). (C and D) dHPC and BLA c-Fos, Arc, and Npas4 expression in the Pre and Alt-Pre groups was significantly elevated above HC levels (ps < .01). # indicates significant elevation above HC; * indicates a significant difference between Pre and Alt-Pre.