Figure 4.

Putative A. massiliense peptide uptake, peptide/amino acid metabolism and PKS synthesis functions. The schematic contains protein names in red (short names as annotated in strain ACS-171-V-Col2 database or for orthologs) and/or gene loci (gene locus prefix HMPREF9233_ is not added to the five-digit accession number). The metabolite names are given in black, blue arrows show an enzymatic activity, black arrows a transport activity, and hatched black arrows a cofactor contribution to an enzyme. We provide approximate abundance values of the in vivo detected proteins using circles (behind their names). The darker the fill color, the higher the average abundance level of a protein in averaged in vivo datasets. Proteins predicted to contain cofactors (based on evidence from characterized orthologs) have green symbols underneath/behind the protein names: Me²⁺ (metal ion), Zn²⁺ (zinc), py (pyridoxal-5’-phosphate). Other acronyms: ABC, ABC transporter; Lys, Met, Thr, Aro (aromatic acid) BS, enzymes involved in the biosynthesis of amino acids.