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. 2018 Nov 1;293(51):19874–19885. doi: 10.1074/jbc.RA118.002768

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© 2018 Tandon et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 1. — Determination of toxicity of TR-433. a, dose-dependent hemolysis of human red blood cells in the presence of TR-433 and melittin. b, the viability of murine 3T3 cells in the presence of TR-433 by an MTT assay. Data are representative of the average of three independent experiments (n = 3) performed in duplicates. Results are given as mean ± S.E. (error bars). c, percentage survival of BALB/c mice (n = 6) after administering (intravenously) 100 and 200 μg of TR-433/animal/day for 3 days.