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. 2018 Sep 3;11(1):7–14. doi: 10.1093/inthealth/ihy060

Table 2.

Representation of males and females defined as G6PD deficient, assuming different thresholds for deficiency. The prevalence of G6PD deficiency is expressed in terms of hemizygous males with a G6PD-deficient allele. The numbers are calculated for a population of 10,000 with equal male and female distribution

Male G6PD deficiency prevalence Threshold G6PD activity expressed as percent of normal
30% 40% 60% 70% 80%
M F T M F T M F T M F T M F T
0.1% No. 5 1 6 5 12 17 22 117 139 106 285 391 417 578 995
% def. 83 17 100 29 71 100 16 84 100 27 73 100 42 58 100
% pop. 0.1 0.0 0.1 0.1 0.2 0.2 0.4 2.3 1.4 2.1 5.7 3.9 8.3 11.6 10.0
1% No. 50 8 58 50 32 82 67 167 234 151 349 500 458 652 1110
% def. 86 14 100 61 39 100 29 71 100 30 70 100 41 59 100
% pop. 1.0 0.2 0.6 1.0 0.6 0.8 1.3 3.3 2.3 3.0 7.0 5.0 9.2 13.0 11.1
5% No. 250 54 304 250 124 374 267 379 646 350 619 969 639 952 1591
% def. 82 18 100 67 33 100 41 59 100 36 64 100 40 60 100
% pop. 5.0 1.1 3.0 5.0 2.5 3.7 5.3 7.6 6.5 7.0 12.4 9.7 12.8 19.0 15.9
10% No. 500 124 624 500 237 737 517 656 1173 595 968 1563 864 1313 2177
% def. 80 20 100 68 32 100 44 56 100 38 62 100 40 60 100
% pop. 10.0 2.5 6.2 10.0 4.7 7.4 10.3 13.1 11.7 11.9 19.4 15.6 17.3 26.3 21.8
20% No. 1000 335 1335 1000 513 1513 1016 1191 2207 1086 1608 2694 1328 1984 3312
% def. 75 25 100 66 34 100 46 54 100 40 60 100 40 60 100
% pop. 20.0 6.7 13.4 20.0 10.3 15.1 20.3 23.8 22.1 21.7 32.2 26.9 26.6 39.7 33.1

For each prevalence, the total number (No.) of males (M), females (F), and the sum of the two (T) that have less than the threshold G6PD activity levels are given.

The relative proportions of the two genders from the total number of deficient (% def.) as well as the proportion (% pop.) of all males, all females, and the total population are also given.