TABLE 3.

Multivariable regression analysis demonstrating the positive association of serum paraoxonase-1 activity with an elevated FLI (≥60) after adjusting for clinical and laboratory covariates in 7,622 subjects

	Model 1a		Model 2b		Model 3c
	β	P	β	P	β	P
Age	−0.106	<0.001	−0.097	<0.001	−0.124	<0.001
Sex (men vs. women)	−0.074	<0.001	−0.094	<0.001	−0.100	<0.001
FLI ≥60 vs. <60	0.043	<0.001	0.083	<0.001	0.064	<0.001
T2D (yes/no)			−0.032	0.007
MetS (yes/no)			−0.066	<0.001
Alcoholic intake ≥10 g/day			0.088	<0.001	0.069	<0.001
Current smoking (yes/no)			−0.078	<0.001	−0.059	<0.001
Elevated blood pressure					0.023	0.083
Enlarged waist					−0.006	0.67
Elevated glucose					−0.037	0.002
Low HDL cholesterol					−0.183	<0.001
Elevated triglycerides					0.088	<0.001

^aAdjusted for age and sex.

^bAdjusted for age, sex, T2D, MetS, alcohol consumption, and current smoking.

^cAdjusted for age, sex, waist circumference, and individual MetS criteria (elevated blood pressure, enlarged waist, elevated glucose, low HDL cholesterol).