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. Author manuscript; available in PMC: 2019 Oct 2.
Published in final edited form as: Structure. 2018 Aug 16;26(10):1337–1345.e3. doi: 10.1016/j.str.2018.07.005

Figure 5. Sequences of the D4 loop of phosphoglucomutase in diverse eukaryotic organisms.

Figure 5.

Top: a multiple sequence alignment (spanning residues 503 to 515 of human PGM) highlighting identical residues with red background. Bottom: A consensus Web Logo (Crooks et al., 2004) of the D4 loop. R503 and R515 are highlighted by yellow star; variants relevant to this study are indicated with arrows at bottom. Those with confirmed roles in PGM1 deficiency are marked with an asterisk.