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Effect of TLR9 to chemoresistance by hypoxia.
Notes: (A) TLR9 agonist CpG ODN2006 reduces the sensitivity of SKOV3 to cisplatin; (B) TLR9 antagonist attenuates hypoxia supernatant-induced cell resistance to cisplatin. *P<0.01, compared with control group.
Abbreviations: HICR, hypoxia-induced chemoresistance; CQ, chloroquine.
