Table 2.

Significant immune pathway prognostic effects

Pathways (N = 48)	Genes	INHALE GSEA		TCGA Lung GSEA
		Enrichment score	P valuea	Enrichment score	P valuea
MHC Class II Family	121	0.51	0.004	0.39	0.504
Interleukin Signaling	430	0.44	0.008	0.44	0.039
Advanced Glycosylation Receptor Signaling	13	0.66	0.025	0.39	0.733

^aGSEA was ranked and weighted by each gene-level Wald statistic; significance was assessed with 1000 phenotype permutations.