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. Author manuscript; available in PMC: 2019 Jan 2.
Published in final edited form as: Nat Rev Drug Discov. 2016 Dec 2;16(1):19–34. doi: 10.1038/nrd.2016.230

Figure 2.

Figure 2

Innovation patterns in therapeutic areas. Each node in the inner ring corresponds to a drug represented by its ATC code(s). The inner ring corresponds to the level 1 of the ATC code (see Table 2) scaled to the number of drugs in that category. The outer ring represents the level 3 of the ATC code. Each of the subsequent histograms illustrates the number of drugs (small molecules and biologics) distributed per year of first approval per level 3 of the ATC code. Max histogram scale: 100. The approval year refers to the first known worldwide approval date, if available, otherwise the first FDA approval date.