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. Author manuscript; available in PMC: 2019 Jan 2.
Published in final edited form as: Nat Rev Drug Discov. 2016 Dec 2;16(1):19–34. doi: 10.1038/nrd.2016.230

Table 1.

Molecular targets of FDA approved drugs

Targets Drugs
Drug target Class Total targets Small-molecule drug targets Biologic drug target Total drugs Small molecules Biologics
Human Protein 667 549 146 1194 999 195
Pathogen Protein 189 184 7 220 215 5
Other human biomolecules 28 9 22 98 63 35
Other pathogen biomolecules 9 7 4 79 71 8