Fig. 4.

LeX mimetics enhance neurite outgrowth of cerebellar granule cells. Representative images of primary cultured cerebellar granule cells treated only with vehicle DMSO (control), or treated with the LeX mimetic compounds. Bar diagram shows average longest neurite lengths (300 neurons from six wells out of three independent experiments, mean + SEM) exposed to different concentrations of the linear LeX glycomimetic peptide (LeX) or the LeX mimetic compounds. Asterisks signify differences versus vehicle control (control) as determined by one-way ANOVA with Fisher’s PLSD test (F =27.744, p < 0.0001; PLSD *p < 0.05). Scale bar, 20 μm