Table 2.

Prevalence of gastrointestinal symptoms in POTS patients

Author (s)	Title	Population(n)	Gastrointestinal symptoms	GI motility studies
Lawal et al. (2007)[35]	Rapid Gastric Emptying Is More Common than Gastroparesis in Patients With Autonomic Dysfunction	61 POTS (all with mild to moderate CASS*)	49(80%) Nausea, 28(46%) Vomiting, 54 (67%) Abdominal pain	27 (44.2%) Rapid, 17 (27.9) Delayed, 17 (27.9) Normal
Antiel et al. (2008)[6]	Orthostatic Intolerance and Gastrointestinal Motility in Adolescents With Nausea and Abdominal Pain	21 POTS (24% with abnormal sudomotor function)	15 (71%) Nausea, 10 (47%) Vomiting, 14 (67%) Abdominal pain	5 (24%) Rapid, 4 (19%) Delayed, 12 (57%) Normal
Wang et al. (2015)[64]	Gastrointestinal dysfunction in postural tachycardia syndrome	28 POTS	24 (86%) Nausea, 11 (40%) Vomiting, 20 (70%) Abdominal pain	NA
Loavenbruck et al. (2015)[37]	Ehlers Danlos syndrome and gastrointestinal manifestations: a 20-year experience at Mayo Clinic.	163 POTS (36% with abnormal sudomotor function)	34 (21%) Nausea, 16 (10%) Vomiting	78 (48%) Rapid, 30 (18%) Delayed, 5 (34%) Normal
Park et al. (2013)[46]	Gastric emptying in postural tachycardia syndrome: a preliminary report.	22 POTS (32% with abnormal sudomotor function)	18 (82%) Nausea or vomiting, 8 (59%) Abdominal pain	6 (27%) Rapid, 2 (9%) Delayed, 14 (63%) Normal
Al-Shekhlee et al. (2005)[5]	The value of autonomic testing in postural tachycardia syndrome	19 neuropathic-POTS/38 non-neuropathic POTS	13 (68%)/10(26%) Combined symptoms (nausea and vomiting)	NA

^*CASS, composite autonomic scoring scale