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. 2019 Jan 7;218(1):285–298. doi: 10.1083/jcb.201804106

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© 2018 Ratcliffe et al.

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Figure 2. — Diglycine cytohesin-1 regulates HGF-dependent cell migration and invasion. (A) Domain organization of CYTH1. (B) PSI values of cytohesin-1, cytohesin-2, or cytohesin-3 microexons in HeLa, MDA-MB-231, and HCC1143 cell lines. (C) Random cell migration of pLVX empty vector or eGFP-CYTH1 variant expressing cells treated with or without HGF. (D) Representative images of invasion of DAPI stained cell lines. (E) Quantification of experiments shown in D as distance from seeded area. Scale bar, 100 µm. All quantified data indicate mean values ± SEM from three independent experiments. *, P < 0.05; ***, P < 0.001.