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. 2019 Jan 7;218(1):333–349. doi: 10.1083/jcb.201802148

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© 2018 Jürgensen et al.

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Figure 8. — Hyperplastic alveolar epithelial cells express high levels of the collectin SP-A and the surfactant-associated SP-C. (A and B) Immunostaining for SP-A (left) and SP-C (right) in sections of nonfibrotic alveolar tissue (A; arrows highlight positive cells in alveolar wall) and fibrotic tissue in patients with IPF. The number and type of tissue specimens included in the analysis are described in the legend to Fig. 7. Like for SP-D, a strong staining for SP-A and SP-C was observed in hyperplastic alveolar epithelial cells (a) in close proximity with active fibrosing subepithelial fibroblast foci (f).