Figure 6.
Loss of CCP1 does not affect the protein expression levels of mitochondrial fission and fusion factors in pcd mice. (A) Immunoblot analysis of cerebellar protein lysates from 5.5-mo-old pcd homozygous null mice (−/−) and WT littermate controls for CCP1 and various mitochondrial fission and fusion factors. HEK293 cell overexpression (o.e.) of CCP1 served as a positive control. β-Actin and α-tubulin served as respective loading controls for immunoblots shown above. (B) Expression levels of the different mitochondrial fission and fusion factors were quantified by densitometry. Two-tailed t test: P = NS; n = 3 mice per genotype. Error bars are SEM.