Table 1. Characteristics of the study population.
| NC | CLL | CLL | CLL | |
|---|---|---|---|---|
| normal C5 | abnormal C5 | |||
| n | 15 | 40 | 23 | 17 |
| Gender (male/female) | 8/7 | 26/14 | 14/9 | 12/5 |
| Age (Years) | 53±2* | 67±3 | 69±4 | 64±6 |
| Binet Stage (A/B/C) | 28/8/4 | 7/4/2 | 11/4/2 | |
| [%A/%B/%C] | [70/20/10] | [74/17/9] | [65/23/12] | |
| Serum C3 (mg/dl) | 120±6 | 151±4# | 142±7 | 163±8# |
| Above / Below normal range | 0 / 0 | 6 / 1 | 2 / 1 | 4 / 0 |
| % above / % below range | 0 / 0 | 15 / 2.5 | 8.7 / 4.3 | 23 / 0 |
| Serum C4 (mg/ dl) | 28.5±2.1 | 31.2±1.6 | 28.5±2.0 | 34.5±2.2 |
| Above / Below normal range | 0 / 0 | 0 / 1 | 0 / 1 | 0 / 0 |
| % above / % below range | 0 / 0 | 0 / 2.5 | 0 / 4.3 | 0 / 0 |
| Beta 2-microglobulin (mg/dl) | nd | 2.3±0.2 | 2.2±0.3 | 2.2±0.2 |
| Serum lipid profile | ||||
| Cholesterol (mg/dl) | 203±8 | 166±10 | 172±12 | 159±17 |
| Triglycerides (mg/dl) | 123±26 | 151±15 | 139±14 | 164±27 |
| HDL-Cholesterol (mg/dl) | 51±3 | 32.9±2.0# | 36.2±2.8# | 29.2±2.5# |
| Calculated LDL (mg/dl) | 136±8 | 106±8# | 110±11 | 101±13 |
| Non-HDL Chol. (mg/dl) | 152±8 | 137±10 | 138±12 | 135±17 |
All values are given as mean ± SEM.
* indicates significant p value (p<0.003) compared to each of the other groups.
# indicates significant p value (p<0.05) compared to the NC group.