Table 4. Blood parameters pre- and post-fasting.

	All (n = 1422)		F5d 5±2 d		F10d 10±2 d		F15d 15±2 d		F20d 20±2 d		p-values
	pre	post	pre	post	pre	post	Pre	post	pre	post	fasting inter- vention	fasting dura- tion group	sex	fasting dura- tion group-by-fasting inter- vention	fasting inter- vention-by-sex
INR	0.99±0.00	1.08±0.00	0.98±0.00	1.06±0.00	0.99±0.01	1.09±0.01	0.99±0.02	1.11±0.02	0.98±0.01	1.10±0.02	<0.001	<0.001	0.84	<0.001	‒
Quick, %	104.3±0.3	91.4±0.3	104.2±0.5	92.9±0.4	104.0±0.6	90.6±0.5	105.6±1.0	89.1±0.9	104.1±1.2	88.3±1.9	<0.001	<0.001	0.33	<0.001	0.005
PTT, sec	31.1±0.1	32.7±0.1	31.1±0.1	32.4±0.1	31.0±0.1	32.8±0.2	31.2±0.2	33.7±0.3	31.4±0.4	32.9±0.5	<0.001	<0.001	0.88	<0.001	‒
GOT, μkat/L	0.4±0.0	0.6±0.0	0.4±0.0	0.6±0.0	0.4±0.0	0.6±0.0	0.4±0.0	0.6±0.0	0.4±0.0	0.7±0.0	<0.001	0.73	0.007	‒	<0.001
GPT, μkat/L	0.5±0.0	0.7±0.0	0.5±0.0	0.6±0.0	0.5±0.0	0.7±0.0	0.5±0.0	0.7±0.0	0.6±0.0	0.8±0.1	<0.001	0.07	0.65	0.10	‒
GGT, μkat/L	0.6±0.0	0.4±0.0	0.5±0.0	0.4±0.0	0.6±0.1	0.4±0.0	0.6±0.1	0.4±0.0	0.5±0.1	0.4±0.01	<0.001	<0.001	0.18	<0.001	<0.001
AP, μkat/L	1.1±0.0	1.0±0.0	1.0±0.0	1.0±0.0	1.1±0.0	1.1±0.0	1.1±0.0	1.0±0.0	1.2±0.1	1.1±0.1	<0.001	<0.001	0.003	<0.001	0.002
CRP, mg/L	2.85±0.14	4.30±0.20	2.49±0.19	4.11±0.27	3.02±0.28	4.35±0.36	3.37±0.32	4.74±0.63	4.08±0.67	4.67±0.82	0.001	0.97	0.99	0.81	0.53
ESR 1h	11.6±0.2	11.4±0.2	10.9±0.3	11.7±0.3	11.8±0.4	11.5±0.4	12.8±0.7	10.6±0.6	15.1±1.6	10.2±1.4	<0.001	<0.001	0.002	<0.001	<0.001
ESR 2h	21.7±0.4	21.3±0.4	20.4±0.5	21.8±0.5	22.1±0.6	21.4±0.6	23.9±1.1	19.7±1.0	28.2±2.8	20.1±2.4	<0.001	<0.001	<0.001	<0.001	<0.001
Uric acid, μmol/L	338.1±2.3	495.2±4.4	334.0±3.3	481.1±6.0	339.2±3.8	505.5±7.5	345.3±6.4	513.0±13.5	355.9±12.8	505.4±30.6	<0.001	0.01	<0.001	0.01	<0.001
Urea, mmol/L	4.7±0.0	3.1±0.0	4.6±0.1	3.3±0.1	4.7±0.1	3.0±0.1	4.7±0.1	2.7±0.1	5.1±0.3	2.8±0.3	<0.001	<0.001	<0.001	<0.001	<0.001
Creatinine, μmol/L	71.92±0.40	76.43±0.54	72.53±0.58	76.45±0.76	71.88±0.68	76.88±1.00	69.86±0.98	74.98±1.21	72.27±2.53	77.17±3.13	<0.001	0.34	<0.001	‒	<0.001
Na,mmol/L	140.1±0.1	138.7±0.1	140.0±0.1	138.4±0.1	140.1±0.1	138.8±0.1	139.8±0.3	139.2±0.2	141.0±0.33	139.9±0.4	<0.001	<0.001	0.37	0.003	‒
K, mmol/L	4.4±0.0	4.4±0.0	4.4±0.0	4.4±0.0	4.4±0.0	4.4±0.0	4.3±0.0	4.4±0.0	4.4±0.1	4.4±0.1	0.001	0.74	<0.001	‒	0.008
Ca, mmol/L	2.32±0.00	2.38±0.00	2.33±0.00	2.36±0.00	2.32±0.00	2.39±0.00	2.32±0.01	2.39±0.01	2.33±0.02	2.40±0.02	<0.001	<0.001	0.14	<0.001	‒
Mg, mmol/L	0.86±0.00	0.87±0.00	0.87±0.00	0.89±0.00	0.87±0.00	0.87±0.00	0.85±0.00	0.86±0.01	0.86±0.01	0.85±0.01	0.09	<0.001	<0.001	<0.001	<0.001

Values are shown as mean±SEM for all of the groups with different fasting lengths. P-values were calculated for the effects of fasting (fasting intervention) as well as the effects of the fasting length (fasting duration group) and gender (sex). Interactions between fasting intervention by fasting duration group (fasting duration group-by-fasting intervention) and fasting intervention by gender (fasting intervention-by-sex) are shown.

INR, international normalized ratio; PTT, partial thromboplastin time; GOT, serum glutamic oxaloacetic transaminase; GPT, serum glutamate pyruvate transaminase; GGT, serum gamma-glutamyl transferase; AP, alkaline phosphatase; CRP, C-reactive protein; ESR 1h, erythrocyte sedimentation rate after 1 hour; ESR 2h, erythrocyte sedimentation rate after 2 hours; Na, sodium; K, potassium; Ca, calcium, Mg, magnesium