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. 2019 Jan 2;14(1):e0207785. doi: 10.1371/journal.pone.0207785

Table 5. miRNAs with changes related to TBI likelihood.

miRNA TBI Fluid Interaction Change Saliva Change Serum Top Human Tissues Human CSF
miR-7-1-3p 0.147 0.853 0.417 - Fetal CNS, nose, pharynx, lymphoid, adipose
miR-10a-5p 0.136 0.131 0.417 Kidney, stomach, uterus, liver, lung ++++
miR-10b-5p 0.119 0.234 0.739 Uterus, prostate, bladder, breast, head ++++
miR-20a-5p 0.136 0.987 0.396 - Kidney, lymphoid, uterus +
miR-30b-5p 0.136 0.408 0.723 Breast, nose, testes, heart ++
miR-92a-3p 0.119 0.987 0.594 Kidney, fetal CNS, tonsil, adult CNS, lymphocyte ++++
miR-122-5p 0.119 0.024 0.162 - Germ line cells, liver, kidney +++
miR-128-3p 0.147 0.850 0.803 CNS, lung, fetal lung, lymphoid ++
miR-155-5p 0.147 0.589 0.806 - Lymphoid, tonsil, umbilical cord ++
miR-455-5p 0.136 0.803 0.896 Skin, keratinocytes, uterus, heart, liver, cerebellum +
miR-1307-3p 0.147 0.720 0.760 Pharynx, kidney, liver thyroid, head ++
miR-3146 0.119 0.649 0.844 - Lymphocytes, uterus, keratinocytes, kidney, tonsil +
miR-3678-3p 0.147 0.922 0.821 Lymphocyte, Tonsil
miR-376a-5p 0.021 0.535 0.749 - Skin, placenta, heart, CNS, testes +
miR-4637 0.136 0.689 0.516 - Uterus, lymphoid, tonsil, keratinocytes, liver, CNS
miR-4649-3p 0.119 0.091 0.139 - Nose, uterus, foreskin fibroblasts
miR-4693-5p 0.119 0.320 0.812 - ‘-
miR-4766-5p 0.147 0.015 0.139 - Lymphoid, uterus, kidney, liver +
miR-5694 0.147 0.649 0.665 Uterus, breast, brain, spleen, thymus +
miR-6770-5p 0.136 0.235 0.825 - ‘- ++
miR-6809-3p 0.119 0.269 0.668 ‘- +

Note: miRNAs in bold are displayed in subsequent figures. Top expressing tissues referenced from miRGator expression atlas of normal organs (http://mirgator.kobic.re.kr). Human cerebrospinal fluid (CSF) data referenced from Hicks and colleagues [12] based on reads per million (RPM) in control or TBI subject CSF according to log10 expression levels: + (>10 RPM), ++ (>100 RPM), +++ (>1,000 RPM), ++++ (>10,000 RPM).