Table 8. Correlations between changes in miRNA levels (post-fight), HTH, and functional measures.
Hits to the Head | Two Legs Eyes Closed Balance | Digit Span Backwards Balance | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Change | miRNA | All | Saliva | Serum | All | Saliva | Serum | All | Saliva | Serum |
-/+ | miR-10a-5p | 0.013 | 0.149 | 0.031 | -0.146 | -0.029 | -0.206 | -0.006 | -0.002 | 0.036 |
+/+ | miR-10b-5p | -0.583 | 0.273 | -0.610 | -0.147 | 0.078 | -0.228 | 0.202 | 0.294 | 0.012 |
/+ | miR-122-5p | 0.372 | 0.336 | 0.386 | -0.192 | -0.046 | -0.278 | 0.034 | -0.066 | 0.086 |
-/+ | miR-128-3p | 0.280 | 0.355 | 0.268 | 0.040 | 0.076 | 0.026 | 0.079 | -0.011 | 0.157 |
-/+ | miR-1307-3p | 0.237 | 0.474 | 0.185 | -0.102 | -0.018 | -0.145 | -0.061 | 0.000 | -0.070 |
-/+ | miR-155-5p | 0.079 | 0.107 | 0.099 | -0.016 | 0.174 | -0.039 | 0.159 | 0.281 | 0.231 |
+/ | miR-20a-5p | -0.136 | 0.096 | -0.175 | -0.096 | -0.168 | -0.058 | -0.025 | -0.030 | 0.038 |
+/+ | miR-30b-5p | 0.070 | 0.197 | -0.028 | -0.006 | -0.117 | 0.078 | 0.216 | 0.097 | 0.359 |
-/ | miR-3146 | 0.124 | 0.251 | -0.325 | -0.181 | -0.185 | -0.182 | -0.221 | -0.274 | -0.069 |
-/- | miR-3678-3p | 0.421 | 0.658 | -0.096 | 0.095 | 0.120 | 0.091 | 0.007 | 0.049 | 0.004 |
-/ | miR-376a-5p | 0.444 | 0.574 | 0.210 | -0.025 | -0.037 | 0.020 | -0.171 | -0.124 | -0.278 |
-/- | miR-455-5p | 0.254 | 0.36 | 0.118 | -0.189 | -0.187 | -0.215 | -0.195 | -0.211 | -0.176 |
/+ | miR-4637 | -0.210 | 0.023 | -0.250 | 0.089 | -0.009 | 0.159 | -0.019 | -0.253 | 0.298 |
-/ | miR-4649-3p | 0.058 | 0.055 | -0.019 | 0.001 | -0.002 | -0.005 | -0.103 | -0.098 | -0.184 |
/+ | miR-4693-5p | -0.006 | -0.031 | -0.008 | 0.115 | 0.090 | 0.164 | -0.015 | -0.088 | 0.324 |
-/ | miR-4766-5p | 0.060 | 0.488 | 0.043 | -0.063 | -0.045 | -0.385 | -0.098 | -0.121 | 0.324 |
-/- | miR-5694 | 0.055 | -0.258 | 0.094 | -0.058 | 0.027 | -0.180 | -0.037 | 0.067 | -0.204 |
-/ | miR-6770-5p | 0.455 | 0.524 | 0.387 | 0.104 | 0.078 | 0.156 | 0.141 | 0.130 | 0.202 |
-/- | miR-6809-3p | 0.293 | 0.439 | 0.079 | -0.102 | 0.095 | -0.132 | -0.062 | 0.074 | -0.213 |
-/ | miR-7-1-3p | 0.017 | 0.287 | -0.049 | -0.006 | 0.107 | -0.075 | -0.055 | -0.128 | 0.041 |
-/- | miR-92a-3p | 0.300 | 0.412 | -0.013 | -0.105 | -0.184 | -0.001 | -0.122 | -0.151 | 0.005 |
Pearson correlations between HTH values and changes in miRNa levels were adjusted using Bonferroni FDR < 0.05 (bold)
Correlations between TLEC, DSB_Bal and changes in miRNA levels were interpreted without FDR correction (p<0.05)